| Date | Location | Result | |
| 3/9/11 | El Paso, Texas (Don Haskins Center) | Marshall 97, Houston 87 | Box score |
| 3/5/11 | Hofheinz Pavilion (Houston, Texas) | Rice 72, Houston 57 | Box score |
| 3/2/11 | New Orleans, La. (Fogelman Arena) | Tulane 80, Houston 77 | Box score |
| 2/26/11 | Hofheinz Pavilion (Houston, Texas) | UAB 68, Houston 55 | Box score |
| 2/22/11 | Memphis, Tenn. (FedExForum) | Memphis 69, Houston 58 | Box score |
| 2/19/11 | El Paso, Texas (Don Haskins Center) | UTEP 76, Houston 64 | Box score |
| 2/16/11 | Hofheinz Pavilion (Houston, Texas) | SMU 65, Houston 51 | Box score |
| 2/12/11 | Hofheinz Pavilion (Houston, Texas) | Houston 79, Tulane 68 | Box score |
| 2/5/11 | Tulsa, Okla. (Reynolds Center) | Tulsa 76, Houston 71 | Box score |
| 2/1/11 | Hofheinz Pavilion (Houston, Texas) | Marshall 63, Houston 62 | Box score |
| 1/29/11 | Greenville, N.C. (Minges Coliseum) | East Carolina 74, Houston 70 | Box score |
| 1/26/11 | Tudor Fieldhouse - Houston, Texas | Rice 79, Houston 71 | Box score |
| 1/22/11 | Hofheinz Pavilion (Houston, Texas) | UTEP 57, Houston 52 | Box score |
| 1/19/11 | Hofheinz Pavilion (Houston, Texas) | Houston 64, Tulsa 57 | Box score |
| 1/15/11 | Dallas, Texas (Moody Coliseum) | Houston 70, SMU 68 | Box score |
| 1/8/11 | Hofheinz Pavilion (Houston, Texas) | Houston 76, UCF 71 | Box score |
| 1/5/11 | Hattiesburg, Miss. (Reed Green Coliseum) | Southern Miss 85, Houston 73 | Box score |
| 12/30/10 | Hofheinz Pavilion (Houston, Texas) | Houston 85, Rogers State 48 | Box score |
| 12/21/10 | Hofheinz Pavilion (Houston, Texas) | Houston 75, Sam Houston State 73 | Box score |
| 12/18/10 | American Bank Center Corpus Christi, TX) | A&M-Corpus Christi 81, Houston 78 | Box score |
| 12/11/10 | Hofheinz Pavilion (Houston, Texas) | UTSA 68, Houston 63 | Box score |
| 12/6/10 | Hofheinz Pavilion (Houston, Texas) | Houston 64, Nevada 61 | Box score |
| 12/4/10 | Huntsville, Tex. (Johnson Coliseum) | Houston 75, Sam Houston State 71 | Box score |
| 11/30/10 | PMAC (Baton Rouge, LA) | LSU 73, Houston 57 | Box score |
| 11/27/10 | Fort Worth, TX (Daniel-Meyer Coliseum) | TCU 79, Houston 63 | Box score |
| 11/23/10 | Hofheinz Pavilion (Houston, Texas) | Houston 78, Louisiana 65 | Box score |
| 11/20/10 | Hofheinz Pavilion (Houston, Texas) | Houston 81, Northwestern Oklahoma State 58 | Box score |
| 11/17/10 | Ruston, La. (Thomas Assembly Center) | Louisiana Tech 60, Houston 54 | Box score |
| 11/14/10 | Hofheinz Pavilion (Houston, Texas) | Houston 88, Alcorn State 68 | Box score |
| 11/12/10 | Hofheinz Pavilion (Houston, Texas) | Houston 63, Nicholls State 62 | Box score |
