| Date | Location | Result | |
| May 28, 2010 | Houston, Texas | Southern Miss 10, Houston 6 | Box score |
| May 27, 2010 | Houston, Texas | Rice 24, Houston 3 | Box score |
| May 26, 2010 | Houston, Texas | Houston 11, Marshall 7 | Box score |
| May 22, 2010 | Greenville, N.C. | East Carolina 8, Houston 6 | Box score |
| May 21, 2010 | Greenville, N.C. | Houston 7, East Carolina 6 | Box score |
| May 20, 2010 | Greenville, N.C. | Houston 8, East Carolina 6 | Box score |
| May 18, 2010 | Houston, Texas | Rice 15, Houston 5 | Box score |
| May 16, 2010 | Houston, Texas | Houston 10, Marshall 1 | Box score |
| May 15, 2010 | Houston, Texas | Marshall 5, Houston 3 | Box score |
| May 15, 2010 | Houston, Texas | Houston 11, Marshall 6 | Box score |
| May 11, 2010 | Houston, Texas | Texas A&M 12, Houston 3 | Box score |
| May 09, 2010 | Houston, Texas | Tulane 8, Houston 6 | Box score |
| May 08, 2010 | Houston, Texas | Tulane 15, Houston 2 | Box score |
| May 07, 2010 | Houston, Texas | Houston 9, Tulane 7 | Box score |
| May 01, 2010 | Birmingham, Ala. | Houston 7, UAB 4 | Box score |
| May 01, 2010 | Birmingham, Ala. | Houston 16, UAB 11 | Box score |
| Apr 30, 2010 | Birmingham, Ala. | UAB 11, Houston 6 | Box score |
| Apr 28, 2010 | Houston, Texas | Houston 8, Lamar 7 | Box score |
| Apr 27, 2010 | Huntsville, Texas | Sam Houston State 5, Houston 3 | Box score |
| Apr 25, 2010 | Hattiesburg, Miss. | Southern Miss 8, Houston 5 | Box score |
| Apr 24, 2010 | Hattiesburg, Miss. | Southern Miss 13, Houston 4 | Box score |
| Apr 23, 2010 | Hattiesburg, Miss. | Southern Miss 10, Houston 9 | Box score |
| Apr 21, 2010 | Beaumont, Texas | Lamar 7, Houston 6 | Box score |
| Apr 18, 2010 | Houston, Texas | Houston 8, Memphis 6 | Box score |
| Apr 17, 2010 | Houston, Texas | Memphis 8, Houston 2 | Box score |
| Apr 16, 2010 | Houston, Texas | Houston 10, Memphis 7 | Box score |
| Apr 13, 2010 | San Antonio, Texas | Houston 14, UTSA 8 | Box score |
| Apr 11, 2010 | Houston, Texas | TCU 12, Houston 2 | Box score |
| Apr 10, 2010 | Houston, Texas | TCU 6, Houston 1 | Box score |
| Apr 09, 2010 | Houston, Texas | TCU 15, Houston 1 | Box score |
| Apr 06, 2010 | Houston, Texas | Houston 4, Sam Houston State 2 | Box score |
| Apr 03, 2010 | Houston, Texas | Rice 8, Houston 7 | Box score |
| Apr 02, 2010 | Houston, Texas | Rice 11, Houston 2 | Box score |
| Apr 01, 2010 | Houston, Texas | Rice 6, Houston 0 | Box score |
| Mar 30, 2010 | Houston, Texas | UTSA 6, Houston 5 | Box score |
| Mar 28, 2010 | Houston, Texas | Houston 20, UCF 3 | Box score |
| Mar 27, 2010 | Houston, Texas | Houston 7, UCF 3 | Box score |
| Mar 26, 2010 | Houston, Texas | UCF 7, Houston 4 | Box score |
| Mar 23, 2010 | Nacogdoches, Texas | Houston 10, Stephen F. Austin 3 | Box score |
| Mar 21, 2010 | Tempe, Ariz. | Arizona State 6, Houston 5 | Box score |
| Mar 20, 2010 | Tempe, Ariz. | Arizona State 6, Houston 0 | Box score |
| Mar 19, 2010 | Tempe, Ariz. | Arizona State 10, Houston 1 | Box score |
| Mar 17, 2010 | Berkeley, Calif. | Houston 12, California 9 | Box score |
| Mar 16, 2010 | San Francisco, CA | San Francisco 3, Houston 2 | Box score |
| Mar 14, 2010 | San Luis Obispo, CA | Houston 5, Cal Poly 3 | Box score |
| Mar 13, 2010 | San Luis Obispo, CA | Houston 6, Cal Poly 2 | Box score |
| Mar 12, 2010 | San Luis Obispo, CA | Houston 13, Cal Poly 8 | Box score |
| Mar 07, 2010 | Houston, Texas | Houston 15, Texas Tech 8 | Box score |
| Mar 06, 2010 | Houston, Texas | Houston 1, Texas 0 | Box score |
| Mar 05, 2010 | Houston, Texas | Houston 3, Missouri 0 | Box score |
| Mar 02, 2010 | Houston, Texas | Rice 8, Houston 2 | Box score |
| Feb 28, 2010 | Houston, Texas | Santa Clara 8, Houston 7 | Box score |
| Feb 27, 2010 | Houston, Texas | Houston 3, Santa Clara 2 | Box score |
| Feb 26, 2010 | Houston, Texas | Houston 17, Santa Clara 9 | Box score |
| Feb 21, 2010 | Houston, Texas | Texas State 9, Houston 7 | Box score |
| Feb 20, 2010 | Houston, Texas | Texas State 6, Houston 3 | Box score |
| Feb 19, 2010 | Houston, Texas | Texas State 6, Houston 0 | Box score |
